For me it comes real close between Dead Space 2 and Rage. However I have a feeling I may not see Rage come out till late 2011 early 2012. Dead Space 2 looks like it is going to be a lot of fun can't wait.
Fun Fact: Unless you're getting it for PS3, Final Fantasy XIV will be out this September.
Thx Hazel and Costa
Final Fantasy XIV
I am enraged at Square Enix's antics as far as this whole "chocobo = horsebird" thing goes. I probably won't be buying anymore games from them for the sole reason that this is ridiculous and tradition raping, also the most efficient and expensive troll in history.
I know. O.o Makes me not want to play it. 
Horse bird sounds so stupid.
Reach and new vegas
that is all
Alt+F4 to unlock the command prompt
Reach and new vegas
that is all
Halo Reach - September 14, 2010
Fallout: New Vegas - October 19, 2010
Then again, it's pretty shitty to ask what your most anticipated games for next year in the summer anyway.
Thx Hazel and Costa
Lol sevlag. Reach is my most anticipated game this year. Next year it has to be Dead Space 2. got all achievements on Dead Space. I LOVE THAT GAME.
reach
metal gear rising
castlevania lords of shadow
get sum.
Lords of Shadows is coming out this October, and yes I will most likely wait for PS3 FFXIV since I am sure i wont have a good computer before March.
Gran Turismo 5...almost here, will swear it will almost start sounding like Diablo 3 if they delay from 3D
(I just want to play already)
No that was a clone - Dr Hitler Clone
Metal Gear Rising and Final Fantasy XIV
I have only played Metal Gear Online so far but its it has that awesome game feeling, so I'm looking forward to rising. I am a sucker for Final Fantasy games and I never had a chance to play FFXI so I might try my hand at XIV. There are other games i could list but i don't want to list them all.